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analyses have examined exposures related to sex hormones in women as potential protective factors for these tumors, with inconsistent. glioma genome-wide association studies GWAS have not stratified by sex. Datasets were analyzed using sex-stratified logistic regression models and combined using meta-analysis. There were 4, male cases, 5, male controls, 3, female cases and 5, female controls.

A ificant association was detected at rs 7p Association at rs 8q A large region on 3p The identified differences in effect of risk variants do not fully explain the observed incidence difference in glioma by sex. Written informed consent was obtained from all participants. There are no conflicts of interest to report.

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of items displayed: 5 10 15 20 50 Create RSS Cancel. RSS Link Copy. Full text links Cite Display options Display options. Figures Figure 1 Average Annual Incidence of all…. Figure 1 Average Annual Incidence of all glioma, glioblastoma and lower grade glioma by sex…. Figure 2 Study Schematic for analyses of…. Figure 3 Sex-specific odds ratios overall and…. Figure 4 Manhattan plot of -log p values….

Aggression in women: behavior, brain and hormones

Figure 4 Manhattan plot of -log p values for all glioma in A males…. Figure 5 Plot of region on chromosome…. Figure 5 Plot of region on chromosome 3 identified as having a sex-specific association with…. Plot of region on chromosome 3 identified as having a sex-specific association with GBM for A males and B females.

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See this image and copyright information in PMC. Similar articles The association of 6 variants of 8q24 and the risk of glioma: A meta-analysis. Tong Y, et al. Medicine Baltimore. Age-specific genome-wide association study in glioblastoma identifies increased proportion of 'lower grade glioma'-like features associated with younger age. Ostrom QT, et al. Int J Cancer. Epub Sep Deciphering the 8q Enciso-Mora V, et al.

Sex-specific glioma genome-wide association study identifies new risk locus at 3p in females, and finds sex-differences in risk at 8q

Hum Mol Genet. Epub Feb Fine mapping analysis of a region of 20q Song X, et al. Epub Mar 2. PMID: Genome-Wide Association Studies in Glioma. Kinnersley B, et al. Cancer Epidemiol Biomarkers Prev. Epub Jan See all similar articles. Cited by 18 articles Gliomas - An experience based on molecular markers. Sarma S, et al.

J Family Med Prim Care. Epub Apr 8.

Chen CH, et al. Front Oncol. Jalali A, et al. Cancer Res. Epub Mar Carrano A, et al. See all "Cited by" articles. References Ostrom QT, et al. Quantifying the heritability of glioma using genome-wide complex trait analysis. Scientific reports. Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors.